Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) – Pipeline Review, H2 2017

The Report Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) – Pipeline Review, H2 2017 provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. – MarketResearchReports.biz”

Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) pipeline Target constitutes close to 7 molecules. Out of which approximately 7 molecules are developed by Companies. The latest report Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) – Pipeline Review, H2 2017, outlays comprehensive information on the Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.

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Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) – Protein kinase C (PKC) is an enzyme belonging to a family of serine- and threonine-specific protein kinases that is activated by calcium and the second messenger diacylglycerol. This kinase showed involvement in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. The molecules developed by companies in Phase II, Phase I, Preclinical and Discovery stages are 1, 1, 4 and 1 respectively. Report covers products from therapy areas Central Nervous System, Cardiovascular, Genetic Disorders and Oncology which include indications Alzheimer’s Disease, Acid Sphingomyelinase Deficiency (Niemann-Pick Disease) Type C, Alcohol Addiction, Fragile X Syndrome, Head And Neck Cancer, Ischemic Stroke, Neurology, Rett Syndrome and Traumatic Brain Injury.

Furthermore, this report also reviews key players involved in Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

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Scope

– The report provides a snapshot of the global therapeutic landscape for Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13)

– The report reviews Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources

– The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages

– The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities

– The report reviews key players involved in Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) targeted therapeutics and enlists all their major and minor projects

– The report assesses Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type

– The report summarizes all the dormant and discontinued pipeline projects

– The report reviews latest news and deals related to Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) targeted therapeutics

Reasons to buy

– Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies

– Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

– Identify and understand the targeted therapy areas and indications for Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13)

– Identify the use of drugs for target identification and drug repurposing

– Identify potential new clients or partners in the target demographic

– Develop strategic initiatives by understanding the focus areas of leading companies

– Plan mergers and acquisitions effectively by identifying key players and its most promising pipeline therapeutics

– Devise corrective measures for pipeline projects by understanding Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) development landscape

– Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

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Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) – Overview 6

Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) – Therapeutics Development 7

Products under Development by Stage of Development 7

Products under Development by Therapy Area 8

Products under Development by Indication 9

Products under Development by Companies 10

Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) – Therapeutics Assessment 12

Assessment by Mechanism of Action 12

Assessment by Route of Administration 14

Assessment by Molecule Type 16

Protein Kinase C Epsilon Type (nPKC Epsilon or PRKCE or EC 2.7.11.13) – Drug Profiles 17

Bryostatin-1 – Drug Profile 17

Product Description 17

Mechanism Of Action 17

R&D Progress 17

Small Molecule to Activate Epsilon PKC for Ischemic Stroke – Drug Profile 23

Product Description 23

Mechanism Of Action 23

R&D Progress 23

Small Molecule to Activate Epsilon PKC for Traumatic Brain Injury – Drug Profile 24

Product Description 24

Mechanism Of Action 24

R&D Progress 24

Small Molecule to Activate PKC Epsilon for Neurology – Drug Profile 25

Product Description 25

Mechanism Of Action 25

R&D Progress 25

Small Molecules to Activate PRKCE for Alzheimer’s Disease – Drug Profile 26

Product Description 26

Mechanism Of Action 26

R&D Progress 26

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